What Is Naproxen Sodium Used For

Uses
- What Is Naproxen and How Does It Piece of work?
Dosage
- What Are the Dosages of Naproxen?
Side Furnishings
- What Are Side Effects Associated with Using Naproxen?
Drug Interactions
- What Other Drugs Interact with Naproxen?
Warnings and Precautions
- What Are Warnings and Precautions for Naproxen?

What Is Naproxen and How Does It Work?

Naproxen is used as a treatment to relieve hurting from various conditions such as headaches, musculus aches, tendonitis, dental hurting, and menstrual cramps. It also reduces hurting, swelling, and joint stiffness caused by conditions such as arthritis, bursitis, and gout attacks.

Naproxen belongs to a grade of medications chosen nonsteroidal anti-inflammatory drugs NSAIDs. NSAIDs are a blazon of medications that work by blocking your trunk'southward production of certain natural substances that cause inflammation.

Naproxen is bachelor under the following different brand names: Aleve, EC Naprosyn, Anaprox, Anaprox DS, Naprosyn, Naprox Sodium, Naproxen EC, Naproxen SR, Naprelan, and Menstridol.

What Are the Dosages of Naproxen?

Dosages of Naproxen:

Adult and pediatric:

Tablet

220 mg (over the counter)
250 mg
275 mg
375 mg
500 mg
550 mg

Tablet delayed release

375 mg
500 mg

Tablet, extended-release

375 mg
500 mg
750 mg

Sheathing

220 mg

Oral Suspension

25 mg/ml

Dosage Considerations – Should exist Given as Follows:

Adult Dosage Considerations

Hurting

500 mg orally initially, and then 250 mg orally every 6-8 hours or 500 mg orally every 12 hours every bit needed, non to exceed 1250 mg/day naproxen base on day 1, subsequent daily doses should not exceed 1000 mg naproxen base.
Extended-release 750-chiliad mg orally every day, may temporarily increase to 1500 mg/day if tolerated well and clinically indicated.

Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis

500-chiliad mg/twenty-four hour period orally divided every 12 hours, may increase to 1500 mg/day if tolerated well for a express time.

Dysmenorrhea

500 mg orally initially, and so 250 mg orally every 6-8 every hour or 500 mg orally every 12 hours (long-acting formula), not to exceed 1250 mg/day on the beginning twenty-four hours, subsequently does should not exceed chiliad mg/mean solar day naproxen base.

Gout, Acute

750 mg orally initially, followed by 250 mg every 8 hours until attach subsides
Extended-release 1000-1500 mg every day, followed by 1000 mg every day until the set on subsides

Migraine (Off-characterization)

750 mg orally initially, may requite boosted 250-500 mg if necessary, not to exceed 1250 mg in 24 hours

Pediatric Dosage Considerations

Pain

Over 2 years
Cancer pain (off-characterization): v-7 mg/kg orally every 8-12 hours, not to exceed chiliad mg per twenty-four hours.
Over 12 years
500 mg orally initially, then 250 mg orally every 6-8 hours or 500 mg orally every 12 hours as needed, non to exceed 1250 mg per day naproxen base on mean solar day i, subsequent daily doses should non exceed yard naproxen base.
Extended-release: 750-grand mg orally each day; may temporarily increase to 1500 mg/solar day if tolerated well and clinically indicated

Juvenile Idiopathic Arthritis

Over 2 years
10 mg/kg/24-hour interval oral break orally divided every 12 hours, non to exceed 15 mg/kg per 24-hour interval

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What Are Side Effects Associated with Using Naproxen?

Common side effects include:

abdominal pain
constipation
dizziness
drowsiness
headache
heartburn
nausea
swelling
intestinal haemorrhage
abdominal perforation
lightheadedness
abdominal ulcers
fluid memory
diarrhea
inflammation of the mucous membrane of the mouth
diverticulitis
difficulty breathing
hearing disturbances
elevation of serum alanine aminotransferase or aspartate aminotransferase

This certificate does not comprise all possible side effects and others may occur. Bank check with your doctor or other medical professional person for additional information about side furnishings or other concerns well-nigh conditions related to your health.

What Other Drugs Interact with Naproxen?

If your md has directed you to use this NSAID, your medical doctor or chemist may already be aware of any possible drug interactions and may be monitoring you for them. Practice not start, stop, or change the dosage of any medicine earlier checking with your doctor, health intendance provider or pharmacist commencement for more health information.

Naproxen has no known severe interactions with any drugs.

Serious Interactions of Naproxen include:

benazepril
captopril
enalapril
fosinopril
ketorolac
ketorolac intranasal
lisinopril
methotrexate
moexipril
pemetrexed
perindopril
quinapril
ramipril
tacrolimus
trandolapril

Naproxen has moderate interactions with at least 229 dissimilar drugs.

Naproxen has mild interactions with at least 80 different drugs.

This data does non contain all possible interactions. Therefore, earlier using this drug, tell your dr. or pharmacist of all the medications you use. Keep a listing of all your medications with you lot, and share the list with your doctor and pharmacist. Bank check with your medico if you have health questions, concerns, or more than health information.

What Are Warnings and Precautions for Naproxen?

Warnings

Cardiovascular run a risk

Nonsteroidal anti-inflammatory drugs may increase take a chance of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal.
Adventure may increase with duration of utilise.
Patients with existing cardiovascular illness or risk factors for such disease may be at greater hazard.
Nonsteroidal anti-inflammatory drugs are contraindicated for perioperative hurting in setting of coronary avenue bypass graft surgery

Gastrointestinal risk

Nonsteroidal anti-inflammatory drugs increase risk of serious gastrointestinal agin events, including bleeding, ulceration, and gastric or intestinal perforation, which can be fatal
Gastrointestinal adverse events may occur at any time during use and without alert symptoms
Elderly patients are at greater take chances for serious gastrointestinal events

This medication contains naproxen. Do not have Aleve, EC Naprosyn, Anaprox, Anaprox DS, Naprosyn, Naprox Sodium, Naproxen EC, Naproxen SR, Naprelan, or Menstridol if you are allergic to naproxen or whatsoever ingredients contained in this drug.

Go along out of attain of children. In example of overdose, get medical help or contact a Poison Command Center immediately.

Contraindications

Hypersensitivity to naproxen or other H2-receptor antagonists.

Contraindications

Absolute: Aspirin allergy; perioperative pain in setting of coronary avenue bypass graft surgery.
Relative: Haemorrhage disorders, delayed esophageal transit, hepatic affliction, peptic ulcer, renal damage, stomatitis, belatedly pregnancy (may cause premature closure of ductus arteriosus).

Effects of Drug Abuse

None

Short-Term Effects

May cause drowsiness, dizziness, and blurred vision
Come across "What Are Side Furnishings Associated with Using Naproxen?"

Long-Term Effects

Prolonged use may increase the risk of adverse cardiovascular events
Long-term assistants of nonsteroidal anti-inflammatory drugs may result in renal papillary necrosis and other renal injury; patients at greatest risk include elderly individuals, those with impaired renal office, decreased volume of blood in the body, heart failure, liver dysfunction, or salt depletion, and those taking diuretics, angiotensin-converting enzyme inhibitors, or angiotensin-receptor blockers
Come across "What Are Side Effects Associated with Using Naproxen?"

Cautions

Use caution in congestive center failure, high claret pressure, kidney/liver harm, or aspirin-sensitive asthma
May increase chance of aseptic meningitis, especially in patients with systemic lupus erythematosis and mixed connective tissue disorders
Prolonged apply may increase risk of adverse cardiovascular events
May cause systemic allergic reactions, even in patients with no prior exposure to nonsteroidal anti-inflammatory drugs
Long-term administration of nonsteroidal anti-inflammatory drugs may result in renal papillary necrosis and other renal injury; patients at greatest risk include elderly individuals, those with dumb renal function, decreased book of blood in the torso, heart failure, liver dysfunction, or salt depletion, and those taking diuretics, angiotensin-converting enzyme inhibitors, or angiotensin-receptor blockers
May cause drowsiness, dizziness, and blurred vision
Platelet aggregation and adhesion may exist decreased; may prolong haemorrhage time; monitor closely patients with coagulation disorders
May increment risk of elevated potassium levels in the blood in the elderly, renal disease, or diabetics, peculiarly when used together with drugs that increase elevated potassium levels in the blood
May cause serious skin reactions including exfoliative dermatitis, toxic epidermal syndrome, Stevens-Johnson syndrome, and toxic epidermal necrolysis; discontinue therapy at commencement sign of skin rash
May crusade new-onset of hypertension; monitor claret pressure closely throughout therapy
Over-the-counter (OTC) apply non for children under 12 years of age
Withhold for at least 4-vi one-half-lives prior to surgery or dental procedure
Heart failure gamble
- Nonsteroidal anti-inflammatory drugs have the potential to trigger heart failure by prostaglandin inhibition that leads to sodium and h2o retention, increased systemic vascular resistance, and blunted response to diuretics
- Nonsteroidal anti-inflammatory drugs should be avoided or withdrawn whenever possible

Pregnancy and Lactation

Apply naproxen with caution for brusk-term use, if the benefits outweigh risks
Animal studies evidence take a chance and human studies are not nonetheless available or neither beast nor man studies are done
Practise not use naproxen for prolonged periods or after 31-32 weeks of gestation
Just employ naproxen in LIFE-THREATING emergencies when no safer drug is available
At that place is positive evidence of human fetal risk
Quebec Pregnancy Registry identified 4705 women who had spontaneous abortions by 20 weeks' gestation; each case was matched to 10 control subjects (n=47,050) who had not had spontaneous abortions; exposure to not-aspirin nonsteroidal anti-inflammatory drug during pregnancy was documented in approximately vii.v% of cases of spontaneous abortions and approximately 2.6% of controls
Naproxen is excreted in chest milk; its effect on infants is unknown. Naproxen is not recommended if lactating.